Safety of pimecrolimus and tacrolimus in the topical therapy of atopic dermatitis
نویسندگان
چکیده
منابع مشابه
Long-term safety of topical pimecrolimus and topical tacrolimus in atopic blepharoconjunctivitis.
Long-term Safety of Topical Pimecrolimus and Topical Tacrolimus in Atopic Blepharoconjunctivitis Atopic blepharoconjunctivitis (ABC) is an ocular manifestation of atopy with a course similar to that of atopic dermatitis: chronic with exacerbations. Topical corticosteroids are widely used for ABC, but longtermuse has awell-established risk of adverse effects: increase of intraocular pressure (IO...
متن کاملTopical tacrolimus as treatment of atopic dermatitis
Atopic dermatitis (AD) is a common, chronic, relapsing, severely pruritic, eczematous skin disease. The mainstays of treatment for AD are topical tacrolimus and topical steroids. Tacrolimus, a calcineurin inhibitor, not only complements existing treatment options but also overcomes some of the drawbacks of topical steroid therapy when given topically and thus meets the long-term needs of patien...
متن کاملTopical tacrolimus: a new therapy for atopic dermatitis.
Atopic dermatitis is a common problem affecting up to 10 percent of all children. The mainstays of therapy have been oral antihistamines, topical emollients, topical doxepin, and topical corticosteroids. Side effects associated with higher potency topical corticosteroids have limited their use in children and for facial areas. Tacrolimus (Protopic) is an immunosuppressive agent typically used s...
متن کاملAtopic dermatitis: tacrolimus vs. topical corticosteroid use
Atopic dermatitis (AD), the dermatological manifestation of the atopic diathesis, has a variety of clinical presentations. It is a chronic and relapsing inflammatory disorder, requiring a multifaceted treatment approach. Topical corticosteroids are the backbone of therapy. However, concerns over adverse drug reactions associated with their long-term application limit their use. Tacrolimus, on t...
متن کاملEfficacy and tolerability of topical pimecrolimus and tacrolimus in the treatment of atopic dermatitis: meta-analysis of randomised controlled trials.
OBJECTIVE To determine the efficacy and tolerability of topical pimecrolimus and tacrolimus compared with other treatments for atopic dermatitis. DESIGN Systematic review and meta-analysis. DATA SOURCES Electronic searches of the Cochrane Library, Medline, and Embase. STUDY SELECTION Randomised controlled trials of topical pimecrolimus or tacrolimus reporting efficacy outcomes or tolerabi...
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ژورنال
عنوان ژورنال: Medicinski pregled
سال: 2019
ISSN: 0025-8105,1820-7383
DOI: 10.2298/mpns1906139j